(1) Type III intermediate filament protein (57-58 kD) co-expressed with neurofilament triplet proteins.
(2) Photoreceptor-specific glycoprotein found on the rim region of rod outer segment disk membranes. Thought to be essential for assembly, orientation and physical stability of outer segment disks. Predicted sequence 346 residues, highly conserved between rodents, man and cattle. Mutations in the gene (RDS gene: Retinal Degeneration, Slow) can cause retinitis pigmentosa or macular dystrophy.

Dictionary of molecular biology. 2004.

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  • Peripherin 2 — (retinal degeneration, slow), also known as PRPH2, is a human gene.cite web | title = Entrez Gene: PRPH2 peripherin 2 (retinal degeneration, slow)| url = Cmd=ShowDetailView TermToSearch=5961|… …   Wikipedia

  • peripherin — peripherin. См. периферин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Peripherin — protein Name = peripherin caption = width = HGNCid = 9461 Symbol = PRPH AltSymbols = NEF4 EntrezGene = 5630 OMIM = 170710 RefSeq = NM 006262 UniProt = P41219 PDB = ECnumber = Chromosome = 12 Arm = q Band = 12 LocusSupplementaryData =… …   Wikipedia

  • peripherin — A glycoprotein that apparently is needed to maintain the shape of the outer segment disk membranes of rods and cones; it is thought by many investigators that a defect in p. is associated with certain types of blindness. * * * pe·riph·er·in… …   Medical dictionary

  • PRPH — peripherin …   Medical dictionary

  • PRPH — • peripherin …   Dictionary of medical acronyms & abbreviations

  • периферин — peripherin периферин. Цитоскелетный белок (характерен для клеток периферической и, возможно, центральной нервной системы млекопитающих), родственный белкам промежуточных филаментов <intermediate filaments>, вместе с виментином, десмином и… …   Молекулярная биология и генетика. Толковый словарь.

  • Neurofilament — neurofilament, light polypeptide 68kDa Identifiers Symbol NEFL Entrez 4747 HUGO …   Wikipedia

  • ROM1 — Retinal outer segment membrane protein 1, also known as ROM1, is a human gene.cite web | title = Entrez Gene: ROM1 retinal outer segment membrane protein 1| url = Cmd=ShowDetailView… …   Wikipedia

  • Microtubule — Space filling model of a microtubule segment derived from cryo electron microscopy. The protofilaments are seen running along the axis of the segment. The microtubule (+) end is towards the top of the image.[1] Microtubules are a component of the …   Wikipedia

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